Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
- Schmidt, Amand F., Holmes, Michael V., Preiss, David, Swerdlow, Daniel I., Denaxas, Spiros, Fatemifar, Ghazaleh, Faraway, Rupert, Finan, Chris, Valentine, Dennis, Fairhurst-Hunter, Zammy, Hartwig, Fernando Pires, Horta, Bernardo Lessa, Hypponen, Elina, Power, Christine, Moldovan, Max, van Iperen, Erik, Hovingh, Kees, Demuth, Ilja, Norman, Kristina, Steinhagen-Thiessen, Elisabeth, Hancock, Stephen, Attia, John, Holliday, Elizabeth, Scott, Rodney, Teumer, A, Baumeister, S, Doerr, M, Lerch, MM, Voelker, U, Voelzke, H, Ward, J, Pell, JP, Meade, T, Christophersen, IE, Maitland-van der Zee, AH, Baranova, EV, Young, R, Ford, I, Campbell, A, Padmanabhan, S, Bots, ML, Grobbee, DE, Froguel, P, Thuillier, D, Roussel, R, Bonnefond, A, Cariou, B, Smart, M, Bao, Y, Kumari, M, Mahajan, A, Hopewell, JC, Seshadri, S, Dale, C, Costa, RPE, Ridker, PM, Chasman, DI, Reiner, AP, Ritchie, MD, Lange, LA, Cornish, AJ, Dobbins, SE, Hemminki, K, Kinnersley, B, Sanson, M, Labreche, K, Simon, M, Bondy, M, Law, P, Speedy, H, Allan, J, Li, N, Went, M, Weinhold, N, Morgan, G, Sonneveld, P, Nilsson, B, Goldschmidt, H, Sud, A, Engert, A, Hansson, M, Hemingway, H, Asselbergs, FW, Patel, RS, Keating, BJ, Sattar, N, Houlston, R, Casas, JP, Hingorani, AD, Demuth, Juri, Bertram, L, Lill, CM, Coassin, S, Willeit, J, Kiechl, S, Willeit, K, Mason, D, Wright, J, Morris, R, Wanamethee, G, Whincup, P, Ben-Shlomo, Y, McLachlan, S, Price, JF, Kivimaki, M, Welch, C, Sanchez-Galvez, A, Marques-Vidal, P, Nicolaides, A, Panayiotou, AG, Onland-Moret, NC, van der Schouw, YT, Matullo, G, Fiorito, G, Guarrera, S, Sacerdote, C, Wareham, NJ, Langenberg, C, Scott, RA, Luan, J, Bobak, M, Malyutina, S, Pajak, A, Kubinova, R, Tamosiunas, A, Pikhart, H, Grarup, N, Pedersen, O, Hansen, T, Linneberg, A, Jess, T, Cooper, J, Humphries, SE, Brilliant, M, Kitchner, T, Hakonarson, H, Carrell, DS, McCarty, CA, Lester, KH, Larson, EB, Crosslin, DR, de Andrade, M, Roden, DM, Denny, JC, Carty, C, Schofield, P, O'Donnell, M, Yusuf, S, Chong, M, Pare, G, van der Harst, P, Said, MA, Eppinga, RN, Verweij, N, Snieder, H, Christen, T, Mook-Kanamori, DO, Gustafsson, S, Lind, L, Ingelsson, E, Pazoki, R, Franco, O, Hofman, A, Uitterlinden, A, Dehghan, A
- Creator: Schmidt, Amand F. , Holmes, Michael V. , Preiss, David , Swerdlow, Daniel I. , Denaxas, Spiros , Fatemifar, Ghazaleh , Faraway, Rupert , Finan, Chris , Valentine, Dennis , Fairhurst-Hunter, Zammy , Hartwig, Fernando Pires , Horta, Bernardo Lessa , Hypponen, Elina , Power, Christine , Moldovan, Max , van Iperen, Erik , Hovingh, Kees , Demuth, Ilja , Norman, Kristina , Steinhagen-Thiessen, Elisabeth , Hancock, Stephen , Attia, John , Holliday, Elizabeth , Scott, Rodney , Teumer, A , Baumeister, S , Doerr, M , Lerch, MM , Voelker, U , Voelzke, H , Ward, J , Pell, JP , Meade, T , Christophersen, IE , Maitland-van der Zee, AH , Baranova, EV , Young, R , Ford, I , Campbell, A , Padmanabhan, S , Bots, ML , Grobbee, DE , Froguel, P , Thuillier, D , Roussel, R , Bonnefond, A , Cariou, B , Smart, M , Bao, Y , Kumari, M , Mahajan, A , Hopewell, JC , Seshadri, S , Dale, C , Costa, RPE , Ridker, PM , Chasman, DI , Reiner, AP , Ritchie, MD , Lange, LA , Cornish, AJ , Dobbins, SE , Hemminki, K , Kinnersley, B , Sanson, M , Labreche, K , Simon, M , Bondy, M , Law, P , Speedy, H , Allan, J , Li, N , Went, M , Weinhold, N , Morgan, G , Sonneveld, P , Nilsson, B , Goldschmidt, H , Sud, A , Engert, A , Hansson, M , Hemingway, H , Asselbergs, FW , Patel, RS , Keating, BJ , Sattar, N , Houlston, R , Casas, JP , Hingorani, AD , Demuth, Juri , Bertram, L , Lill, CM , Coassin, S , Willeit, J , Kiechl, S , Willeit, K , Mason, D , Wright, J , Morris, R , Wanamethee, G , Whincup, P , Ben-Shlomo, Y , McLachlan, S , Price, JF , Kivimaki, M , Welch, C , Sanchez-Galvez, A , Marques-Vidal, P , Nicolaides, A , Panayiotou, AG , Onland-Moret, NC , van der Schouw, YT , Matullo, G , Fiorito, G , Guarrera, S , Sacerdote, C , Wareham, NJ , Langenberg, C , Scott, RA , Luan, J , Bobak, M , Malyutina, S , Pajak, A , Kubinova, R , Tamosiunas, A , Pikhart, H , Grarup, N , Pedersen, O , Hansen, T , Linneberg, A , Jess, T , Cooper, J , Humphries, SE , Brilliant, M , Kitchner, T , Hakonarson, H , Carrell, DS , McCarty, CA , Lester, KH , Larson, EB , Crosslin, DR , de Andrade, M , Roden, DM , Denny, JC , Carty, C , Schofield, P , O'Donnell, M , Yusuf, S , Chong, M , Pare, G , van der Harst, P , Said, MA , Eppinga, RN , Verweij, N , Snieder, H , Christen, T , Mook-Kanamori, DO , Gustafsson, S , Lind, L , Ingelsson, E , Pazoki, R , Franco, O , Hofman, A , Uitterlinden, A , Dehghan, A
- Resource Type: journal article
- Date: 2019
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- Davies, Gail, Lam, Max, Liewald, David C. M., Knopman, DS, Kochan, NA, Konte, B, Kwok, JB, Le Hellard, S, Lee, T, Lehtimaki, T, Li, S-C, Liu, T, Koini, M, Okely, Judith A., London, E, Longstreth, WT, Lopez, OL, Loukola, A, Luck, T, Lundervold, AJ, Lundquist, A, Lyytikainen, L-P, Martin, NG, Montgomery, GW, Ahola-Olli, Ari V., Murray, AD, Need, AC, Noordam, R, Nyberg, L, Ollier, W, Papenberg, G, Pattie, A, Polasek, O, Poldrack, RA, Psaty, BM, Barnes, Catriona L. K., Reppermund, S, Riedel-Heller, SG, Rose, RJ, Rotter, JI, Roussos, P, Rovio, SP, Saba, Y., Sabb, FW, Sachdev, PS, Satizabal, CL, Bertram, Lars, Schmid, M, Scott, Rodney J., Scult, MA, Simino, J, Slagboom, PE, Smyrnis, N, Soumare, A, Stefanis, NC, Stott, DJ, Straub, RE, Bis, Joshua C., Sundet, K, Taylor, AM, Taylor, KD, Tzoulaki, I, Tzourio, C, Uitterlinden, A, Vitart, V, Voineskos, AN, Kaprio, J, Wagner, M, Burdick, Katherine E., Wagner, H, Weinhold, L, Wen, KH, Widen, E, Yang, Q, Zhao, W, Adams, HHH, Arking, DE, Bilder, RM, Bitsios, P, Christoforou, Andrea, Boerwinkle, E, Chiba-Falek, O, Corvin, A, De Jager, PL, Debette, S, Donohoe, G, Elliott, P, Fitzpatrick, AL, Gill, M, Glahn, DC, DeRosse, Pamela, Hagg, S, Hansell, NK, Hariri, AR, Ikram, MK, Jukema, JW, Vuoksimaa, E, Keller, MC, Kremen, WS, Launer, L, Lindenberger, U, Djurovic, Srdjan, Palotie, A, Pedersen, NL, Pendleton, N, Porteous, DJ, Raikkonen, K, Raitakari, OT, Ramirez, A, Reinvang, I, Rudan, I, Rujescu, D, Harris, Sarah E., Espeseth, Thomas, Schmidt, R, Schmidt, H, Schofield, PW, Schofield, PR, Starr, JM, Steen, VM, Trollor, JN, Turner, ST, Van Duijn, CM, Villringer, A, Giakoumaki, Stella, Weinberger, DR, Weir, DR, Wilson, JF, Malhotra, A, McIntosh, AM, Gale, CR, Seshadri, S, Mosley, TH, Bressler, J, Lencz, T, Giddaluru, S, Deary, IJ, Gustavson, DE, Hayward, C, Hofer, E, Ikram, MA, Karlsson, R, Knowles, E, Lahti, J, Trampush, Joey W., Leber, M, Li, S, Mather, KA, Melle, I, Morris, D, Oldmeadow, Christopher, Palviainen, T, Payton, A, Pazoki, R, Petrovic, K, Luciano, Michelle, Reynolds, CA, Sargurupremraj, M, Scholz, M, Smith, JA, Smith, AV, Terzikhan, N, Thalamuthu, A, Trompet, S, van der Lee, SJ, Ware, EB, Hill, W. David, Windham, BG, Wright, MJ, Yang, J, Yu, J, Ames, D, Amin, N, Amouyel, P, Andreassen, OA, Armstrong, NJ, Assareh, AA, Hagenaars, Saskia P., Attia, John R., Attix, D, Avramopoulos, D, Bennett, DA, Boehmer, AC, Boyle, PA, Brodaty, H, Campbell, H, Cannon, TD, Cirulli, ET, Ritchie, Stuart J., Congdon, E, Conley, ED, Corley, J, Cox, SR, Dale, AM, Dehghan, A, Dick, D, Dickinson, D, Eriksson, JG, Evangelou, E, Marioni, Riccardo E., Faul, JD, Ford, I, Freimer, NA, Gao, H, Giegling, I, Gillespie, NA, Gordon, SD, Gottesman, RF, Griswold, ME, Gudnason, V, Fawns-Ritchie, Chloe, Harris, TB, Hartmann, AM, Hatzimanolis, A, Heiss, G, Holliday, Elizabeth G., Joshi, PK, Kahonen, M, Kardia, SLR, Karlsson, I, Kleineidam, L
- Creator: Davies, Gail , Lam, Max , Liewald, David C. M. , Knopman, DS , Kochan, NA , Konte, B , Kwok, JB , Le Hellard, S , Lee, T , Lehtimaki, T , Li, S-C , Liu, T , Koini, M , Okely, Judith A. , London, E , Longstreth, WT , Lopez, OL , Loukola, A , Luck, T , Lundervold, AJ , Lundquist, A , Lyytikainen, L-P , Martin, NG , Montgomery, GW , Ahola-Olli, Ari V. , Murray, AD , Need, AC , Noordam, R , Nyberg, L , Ollier, W , Papenberg, G , Pattie, A , Polasek, O , Poldrack, RA , Psaty, BM , Barnes, Catriona L. K. , Reppermund, S , Riedel-Heller, SG , Rose, RJ , Rotter, JI , Roussos, P , Rovio, SP , Saba, Y. , Sabb, FW , Sachdev, PS , Satizabal, CL , Bertram, Lars , Schmid, M , Scott, Rodney J. , Scult, MA , Simino, J , Slagboom, PE , Smyrnis, N , Soumare, A , Stefanis, NC , Stott, DJ , Straub, RE , Bis, Joshua C. , Sundet, K , Taylor, AM , Taylor, KD , Tzoulaki, I , Tzourio, C , Uitterlinden, A , Vitart, V , Voineskos, AN , Kaprio, J , Wagner, M , Burdick, Katherine E. , Wagner, H , Weinhold, L , Wen, KH , Widen, E , Yang, Q , Zhao, W , Adams, HHH , Arking, DE , Bilder, RM , Bitsios, P , Christoforou, Andrea , Boerwinkle, E , Chiba-Falek, O , Corvin, A , De Jager, PL , Debette, S , Donohoe, G , Elliott, P , Fitzpatrick, AL , Gill, M , Glahn, DC , DeRosse, Pamela , Hagg, S , Hansell, NK , Hariri, AR , Ikram, MK , Jukema, JW , Vuoksimaa, E , Keller, MC , Kremen, WS , Launer, L , Lindenberger, U , Djurovic, Srdjan , Palotie, A , Pedersen, NL , Pendleton, N , Porteous, DJ , Raikkonen, K , Raitakari, OT , Ramirez, A , Reinvang, I , Rudan, I , Rujescu, D , Harris, Sarah E. , Espeseth, Thomas , Schmidt, R , Schmidt, H , Schofield, PW , Schofield, PR , Starr, JM , Steen, VM , Trollor, JN , Turner, ST , Van Duijn, CM , Villringer, A , Giakoumaki, Stella , Weinberger, DR , Weir, DR , Wilson, JF , Malhotra, A , McIntosh, AM , Gale, CR , Seshadri, S , Mosley, TH , Bressler, J , Lencz, T , Giddaluru, S , Deary, IJ , Gustavson, DE , Hayward, C , Hofer, E , Ikram, MA , Karlsson, R , Knowles, E , Lahti, J , Trampush, Joey W. , Leber, M , Li, S , Mather, KA , Melle, I , Morris, D , Oldmeadow, Christopher , Palviainen, T , Payton, A , Pazoki, R , Petrovic, K , Luciano, Michelle , Reynolds, CA , Sargurupremraj, M , Scholz, M , Smith, JA , Smith, AV , Terzikhan, N , Thalamuthu, A , Trompet, S , van der Lee, SJ , Ware, EB , Hill, W. David , Windham, BG , Wright, MJ , Yang, J , Yu, J , Ames, D , Amin, N , Amouyel, P , Andreassen, OA , Armstrong, NJ , Assareh, AA , Hagenaars, Saskia P. , Attia, John R. , Attix, D , Avramopoulos, D , Bennett, DA , Boehmer, AC , Boyle, PA , Brodaty, H , Campbell, H , Cannon, TD , Cirulli, ET , Ritchie, Stuart J. , Congdon, E , Conley, ED , Corley, J , Cox, SR , Dale, AM , Dehghan, A , Dick, D , Dickinson, D , Eriksson, JG , Evangelou, E , Marioni, Riccardo E. , Faul, JD , Ford, I , Freimer, NA , Gao, H , Giegling, I , Gillespie, NA , Gordon, SD , Gottesman, RF , Griswold, ME , Gudnason, V , Fawns-Ritchie, Chloe , Harris, TB , Hartmann, AM , Hatzimanolis, A , Heiss, G , Holliday, Elizabeth G. , Joshi, PK , Kahonen, M , Kardia, SLR , Karlsson, I , Kleineidam, L
- Resource Type: journal article
- Date: 2018
- Creator: Davies, Gail , Lam, Max , Liewald, David C. M. , Knopman, DS , Kochan, NA , Konte, B , Kwok, JB , Le Hellard, S , Lee, T , Lehtimaki, T , Li, S-C , Liu, T , Koini, M , Okely, Judith A. , London, E , Longstreth, WT , Lopez, OL , Loukola, A , Luck, T , Lundervold, AJ , Lundquist, A , Lyytikainen, L-P , Martin, NG , Montgomery, GW , Ahola-Olli, Ari V. , Murray, AD , Need, AC , Noordam, R , Nyberg, L , Ollier, W , Papenberg, G , Pattie, A , Polasek, O , Poldrack, RA , Psaty, BM , Barnes, Catriona L. K. , Reppermund, S , Riedel-Heller, SG , Rose, RJ , Rotter, JI , Roussos, P , Rovio, SP , Saba, Y. , Sabb, FW , Sachdev, PS , Satizabal, CL , Bertram, Lars , Schmid, M , Scott, Rodney J. , Scult, MA , Simino, J , Slagboom, PE , Smyrnis, N , Soumare, A , Stefanis, NC , Stott, DJ , Straub, RE , Bis, Joshua C. , Sundet, K , Taylor, AM , Taylor, KD , Tzoulaki, I , Tzourio, C , Uitterlinden, A , Vitart, V , Voineskos, AN , Kaprio, J , Wagner, M , Burdick, Katherine E. , Wagner, H , Weinhold, L , Wen, KH , Widen, E , Yang, Q , Zhao, W , Adams, HHH , Arking, DE , Bilder, RM , Bitsios, P , Christoforou, Andrea , Boerwinkle, E , Chiba-Falek, O , Corvin, A , De Jager, PL , Debette, S , Donohoe, G , Elliott, P , Fitzpatrick, AL , Gill, M , Glahn, DC , DeRosse, Pamela , Hagg, S , Hansell, NK , Hariri, AR , Ikram, MK , Jukema, JW , Vuoksimaa, E , Keller, MC , Kremen, WS , Launer, L , Lindenberger, U , Djurovic, Srdjan , Palotie, A , Pedersen, NL , Pendleton, N , Porteous, DJ , Raikkonen, K , Raitakari, OT , Ramirez, A , Reinvang, I , Rudan, I , Rujescu, D , Harris, Sarah E. , Espeseth, Thomas , Schmidt, R , Schmidt, H , Schofield, PW , Schofield, PR , Starr, JM , Steen, VM , Trollor, JN , Turner, ST , Van Duijn, CM , Villringer, A , Giakoumaki, Stella , Weinberger, DR , Weir, DR , Wilson, JF , Malhotra, A , McIntosh, AM , Gale, CR , Seshadri, S , Mosley, TH , Bressler, J , Lencz, T , Giddaluru, S , Deary, IJ , Gustavson, DE , Hayward, C , Hofer, E , Ikram, MA , Karlsson, R , Knowles, E , Lahti, J , Trampush, Joey W. , Leber, M , Li, S , Mather, KA , Melle, I , Morris, D , Oldmeadow, Christopher , Palviainen, T , Payton, A , Pazoki, R , Petrovic, K , Luciano, Michelle , Reynolds, CA , Sargurupremraj, M , Scholz, M , Smith, JA , Smith, AV , Terzikhan, N , Thalamuthu, A , Trompet, S , van der Lee, SJ , Ware, EB , Hill, W. David , Windham, BG , Wright, MJ , Yang, J , Yu, J , Ames, D , Amin, N , Amouyel, P , Andreassen, OA , Armstrong, NJ , Assareh, AA , Hagenaars, Saskia P. , Attia, John R. , Attix, D , Avramopoulos, D , Bennett, DA , Boehmer, AC , Boyle, PA , Brodaty, H , Campbell, H , Cannon, TD , Cirulli, ET , Ritchie, Stuart J. , Congdon, E , Conley, ED , Corley, J , Cox, SR , Dale, AM , Dehghan, A , Dick, D , Dickinson, D , Eriksson, JG , Evangelou, E , Marioni, Riccardo E. , Faul, JD , Ford, I , Freimer, NA , Gao, H , Giegling, I , Gillespie, NA , Gordon, SD , Gottesman, RF , Griswold, ME , Gudnason, V , Fawns-Ritchie, Chloe , Harris, TB , Hartmann, AM , Hatzimanolis, A , Heiss, G , Holliday, Elizabeth G. , Joshi, PK , Kahonen, M , Kardia, SLR , Karlsson, I , Kleineidam, L
- Resource Type: journal article
- Date: 2018
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